A central resource for analyzing brain tumor samples
Core 1: Biospecimens Core
['FUNDING_OTHER'] · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · NIH-10930081
This study is working to improve treatments for glioblastoma, a type of brain tumor, by collecting and analyzing samples from both patients and animals to better understand how the tumor behaves and responds to different therapies.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (CAMBRIDGE, UNITED STATES) |
| Trial ID | NIH-10930081 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a core facility that provides important biological samples from both animals and humans to study glioblastoma, a type of brain tumor. It utilizes patient-derived xenografts and genetically engineered mouse models to better understand tumor biology and treatment responses. By analyzing surgical specimens from patients, the research aims to validate findings from animal models and improve the relevance of preclinical studies. The project collaborates with leading neurosurgeons and utilizes a biobank for comprehensive sample collection and analysis.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with glioblastoma who are undergoing surgical treatment.
Not a fit: Patients with other types of brain tumors or those not undergoing surgery may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with glioblastoma.
How similar studies have performed: Previous research using similar animal models and patient-derived samples has shown promise in advancing our understanding of glioblastoma treatment.
Where this research is happening
CAMBRIDGE, UNITED STATES
- MASSACHUSETTS INSTITUTE OF TECHNOLOGY — CAMBRIDGE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SARKARIA, JANN N. — MASSACHUSETTS INSTITUTE OF TECHNOLOGY
- Study coordinator: SARKARIA, JANN N.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.