NIH-funded research NIH-funded research

A center for testing genome editing in rodents

Official title: MU Rodent Testing Center for Somatic Cell Genome Editing

Funded at University of Missouri-Columbia · NIH-10773783 · Data updated 2026-11-12

This study is creating a special center to help scientists test new gene-editing treatments using rats and mice, making it easier to turn these discoveries into real help for people with diseases.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Missouri-Columbia
NIH-funded
Lab location1 site (Columbia, United States)
Project startAugust 15, 2024
Project endJuly 31, 2026
Funding year2024
Award (this year)$423,027
NIH project number1U42OD035739-01
Project IDNIH-10773783 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for benefiting from this research include individuals with genetic disorders that may be targeted by genome editing therapies.

Less likely to help

Patients with conditions that are not amenable to genetic interventions or those who do not have access to clinical trials may not benefit from this research.

What this research studies

This research focuses on developing a specialized center that provides testing services for genome editing technologies using rodent models, particularly rats and mice. The center aims to accelerate the translation of these technologies into clinical applications by offering access to a variety of rodent disease models and ensuring high-quality standards in animal care. The team involved has extensive expertise in animal modeling and comparative medicine, which will enhance the rigor and reproducibility of research outcomes. By facilitating the testing of genetic interventions, this center aims to support advancements in therapeutic strategies for human diseases.

Why it matters

Potential benefit: If successful, this research could lead to more effective gene therapies for various human diseases.

How similar studies have gone: Other research has shown success in using rodent models for testing genome editing technologies, indicating that this approach is promising and not entirely novel.

Where this research is happening

  • University of Missouri-Columbia
    Columbia, United States
    Active

Researchers

  • Principal investigator: Bryda, Elizabeth C — University of Missouri-Columbia
  • Study coordinator: Bryda, Elizabeth C

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.