3D Printed Spinal Cord Tissues for Spinal Cord Injury
3D Bioprinted Spinal Cord Organoids as a Relay System for Spinal Cord Injury
This project explores using 3D printed spinal cord cells and supportive structures to help repair chronic spinal cord injuries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11162332 on NIH RePORTER |
What this research studies
We are working to find new ways to treat chronic spinal cord injury, which currently has no effective cure. Our approach involves creating special 3D printed tissues made from spinal cord cells and a supportive scaffold. We will first refine the materials and design of these printed tissues. Then, we will determine the best way to arrange the cells within the scaffold to create working nerve connections. Finally, we will test if these printed tissues can bridge injured areas in the spinal cord and help restore movement and feeling.
Who could benefit from this research
Good fit: This foundational work is aimed at eventually helping adults living with chronic spinal cord injuries.
Not a fit: Patients without spinal cord injuries or those with acute injuries may not directly benefit from this specific research focus on chronic injury.
Why it matters
Potential benefit: If successful, this work could lead to a new cell transplantation therapy that helps patients recover function after chronic spinal cord injury.
How similar studies have performed: This approach combines advanced 3D bioprinting with cell transplantation, representing a novel and promising strategy for spinal cord repair.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Parr, Ann M — University of Minnesota
- Study coordinator: Parr, Ann M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.