3D printed device to help repair esophageal atresia in newborns

3D printed bioresorbable sleeve device for esophageal atresia repair

NIH-funded research Johns Hopkins University · NIH-10710202

This study is testing a special 3D printed sleeve that helps newborns with a condition called congenital esophageal atresia heal better after surgery, making it easier for their esophagus to recover and reducing the chances of problems later on.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-10710202 on NIH RePORTER

What this research studies

This research focuses on developing a 3D printed bioresorbable sleeve device designed to assist in the surgical repair of congenital esophageal atresia (EA) in newborns. The device aims to improve the healing process of the esophagus after surgery, particularly for those with long-gap EA, where traditional surgical methods are challenging. By using advanced elastomeric materials, the project seeks to reduce complications such as leaks and strictures that can occur post-surgery. The approach involves creating a scaffold that supports the esophagus during recovery, potentially leading to better outcomes for affected infants.

Who could benefit from this research

Good fit: Ideal candidates for this research are newborns diagnosed with congenital esophageal atresia, particularly those with long-gap EA.

Not a fit: Patients who do not have esophageal atresia or those whose condition is not severe enough to require surgical intervention may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve surgical outcomes and quality of life for newborns with esophageal atresia.

How similar studies have performed: Previous research has shown promise in using 3D printed materials for medical applications, suggesting potential success for this innovative approach.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.