11-oxyandrogens' effects on aging
11-Oxyandrogens and Aging: Health Implications
['FUNDING_R01'] · UNIVERSITY OF MICHIGAN AT ANN ARBOR · NIH-11251796
Researchers are measuring 11-oxyandrogen hormone levels in adults to see how those hormones relate to bone breakdown, blood counts, and other signs of aging.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MICHIGAN AT ANN ARBOR (nih funded) |
| Locations | 1 site (ANN ARBOR, UNITED STATES) |
| Trial ID | NIH-11251796 on ClinicalTrials.gov |
What this research studies
From your perspective, the team will collect blood samples and health information from adults to measure levels of 11-oxyandrogens like 11-ketotestosterone. They will compare hormone levels across men and women and different ages and relate them to markers such as bone degradation biomarkers and hemoglobin. The work combines lab hormone measurements with clinical data to map how these adrenal-derived hormones change with age. Findings could clarify whether sustained 11-oxyandrogen production affects bone health, anemia risk, or other age-related changes.
Who could benefit from this research
Good fit: Adults aged 21 and older, both men and women, who can provide blood samples and basic health information are the likely candidates for participation.
Not a fit: People under 21 or those unwilling to provide blood samples or medical information are unlikely to benefit directly from this research.
Why it matters
Potential benefit: If successful, this could identify hormone markers that help predict or guide treatment for age-related bone loss or low blood counts.
How similar studies have performed: Previous research showed 11-oxyandrogens matter in adrenal and androgen-excess conditions, but applying these hormones to normal human aging is relatively new with only preliminary supporting data.
Where this research is happening
ANN ARBOR, UNITED STATES
- UNIVERSITY OF MICHIGAN AT ANN ARBOR — ANN ARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TURCU, ADINA F — UNIVERSITY OF MICHIGAN AT ANN ARBOR
- Study coordinator: TURCU, ADINA F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.