Drug or treatment

Zongertinib clinical trials

• 6Clinical trials
• 30Countries

Newest trials

All recruiting trials (6)

• Zongertinib tablets from two makers: do they behave the same when taken with or without food

  This early study tests whether two different Zongertinib tablet formulations give similar body levels in healthy adults when taken by mouth, with or without food.

  Recruiting Phase 1 Boehringer Ingelheim · Biberach · NCT07789028

• Zongertinib with or without pembrolizumab and platinum chemotherapy in HER2-mutant NSCLC

  This trial tests whether zongertinib can be tolerated when given with platinum-based chemotherapy, with or without pembrolizumab, in adults with advanced HER2-mutant non-squamous NSCLC.

  Recruiting at 19 sites Phase 2 Boehringer Ingelheim · St Leonards, New South Wales and 19 other locations · NCT07486817

• Adjuvant zongertinib versus standard adjuvant care for completely resected Stage II–IIIB HER2 TKD–mutant NSCLC

  This trial tests whether taking oral zongertinib after surgery can help adults with completely resected Stage II–IIIB NSCLC whose tumors have activating HER2 TKD mutations live longer without the cancer coming back.

  Recruiting at 172 sites Phase 3 Boehringer Ingelheim · Fresno, California and 202 other locations · NCT07195695

• Testing Zongertinib for Advanced Cancers with HER2 Alterations

  This study is testing if a new drug called zongertinib can help adults with advanced cancers that have specific HER2 changes, especially after other treatments haven't worked.

  Recruiting at 81 sites Phase 2 Boehringer Ingelheim · Anchorage, Alaska and 92 other locations · NCT06581432

• Finding the right dose of zongertinib for HER2+ cancer treatment

  This study is testing the best dose of zongertinib to see if it can help adults with hard-to-treat HER2+ cancers shrink their tumors.

  Recruiting at 98 sites Phase 1/2 Boehringer Ingelheim · Cerritos, California and 103 other locations · NCT06324357

• Testing zongertinib for advanced cancer with HER2 gene changes

  This study is testing a new drug called zongertinib to see if it can safely shrink tumors in adults with advanced cancer that have changes in the HER2 gene.

  Recruiting at 34 sites Phase 1 Boehringer Ingelheim · Birmingham, Alabama and 84 other locations · NCT04886804

Quick answers

How many clinical trials of Zongertinib are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 30 countries. The most sites are in Germany (6 trials), China (5 trials), France (5 trials), Japan (5 trials), South Korea (5 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1: 2, Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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