Drug or treatment

Tunlametinib clinical trials

• 5Clinical trials
• 1Country

Newest trials

All recruiting trials (5)

• Combo of tunlametinib, pucotenlimab, and hydroxychloroquine in NRAS-mutant melanoma

  This study tests whether adding hydroxychloroquine to tunlametinib and pucotenlimab helps people with NRAS-mutant melanoma.

  Recruiting Phase 2 Sun Yat-sen University · Guangzhou, Guangdong · NCT07750067

• Tunlametinib for NRAS‑mutant advanced melanoma after PD‑1/PD‑L1 therapy

  This study will test whether the oral drug tunlametinib helps adults with NRAS‑mutant advanced melanoma who did not respond to anti‑PD‑1/PD‑L1 therapy.

  Recruiting Phase 4 Fudan University · Shanghai · NCT07445022

• Tunlametinib for NRAS‑mutant non‑melanoma refractory solid tumors

  This trial tests tunlametinib to see if it can shrink or control advanced non‑melanoma solid tumors that have NRAS mutations in patients who have failed standard treatments.

  Recruiting Phase 2 Tianjin Medical University Second Hospital · Tianjin, Tianjin Municipality · NCT07170293

• Tunlametinib for advanced NRAS‑mutant thyroid cancer

  This trial tests whether the MEK inhibitor tunlametinib, alone or with a PD‑1 immunotherapy, can shrink or control tumors in adults with advanced NRAS‑mutant thyroid cancer that is refractory to radioactive iodine.

  Recruiting Phase 2 Fudan University · Shanghai, Shanghai Municipality · NCT06970353

• Comparing tunlametinib capsules with chemotherapy for advanced NRAS-mutant melanoma

  This study is testing if tunlametinib capsules can work better than standard chemotherapy for people with advanced melanoma that has NRAS mutations and who have already tried immunotherapy.

  Recruiting Phase 3 Shanghai Kechow Pharma, Inc. · Beijing, Beijing Municipality · NCT06008106

Quick answers

How many clinical trials of Tunlametinib are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in China. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 4: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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