Drug or treatment
Petosemtamab clinical trials
As of November 12, 2026, Find a Trial lists 3 clinical trials of Petosemtamab that are recruiting, at sites in 9 countries (most in United States (3), Puerto Rico (2), Belgium (1)). By phase: Phase 3 (2), Phase 1/2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 9Countries
Newest trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Petosemtamab plus chemotherapy vs standard chemo plus cetuximab or bevacizumab in RAS/BRAF WT colorectal cancer | Phase 3 | Hot Springs, Arkansas and 4 other locations | Recruiting | Aug 20, 2026 |
| Petosemtamab plus chemotherapy vs cetuximab plus chemotherapy in left-sided unresectable or metastatic colorectal cancer | Phase 3 | Hot Springs, Arkansas and 11 other locations | Recruiting | Jul 14, 2026 |
| Testing a new bispecific antibody for advanced solid tumors | Phase 1/2 | La Jolla, California and 53 other locations | Recruiting | May 16, 2018 |
All recruiting trials (3)
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Petosemtamab plus chemotherapy vs standard chemo plus cetuximab or bevacizumab in RAS/BRAF WT colorectal cancer
This phase 3 trial tests whether adding petosemtamab to standard chemotherapy works better than the usual chemo plus cetuximab or bevacizumab for people with recurrent, unresectable, or metastatic colorectal cancer that is KRAS/NRAS/BRAF wild type.
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Petosemtamab plus chemotherapy vs cetuximab plus chemotherapy in left-sided unresectable or metastatic colorectal cancer
This trial tests whether adding petosemtamab to standard chemotherapy works better than cetuximab with chemotherapy for adults with left-sided, unresectable or metastatic colorectal cancer that is KRAS/NRAS wild-type.
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Testing a new bispecific antibody for advanced solid tumors
This study is testing a new treatment called MCLA-158 to see if it can help people with advanced solid tumors, especially those with metastatic colorectal cancer, when other options have run out.
Quick answers
How many clinical trials of Petosemtamab are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 9 countries. The most sites are in United States (3 trials), Puerto Rico (2 trials), Belgium (1 trial), France (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.