Drug or treatment

Penpulimab clinical trials

• 11Clinical trials
• 1Country

Newest trials

All recruiting trials (11)

• Becotatug Vedotin with or without Immunotherapy before surgery for locally advanced head and neck cancer

  This trial tests Becotatug Vedotin alone or together with immune checkpoint inhibitors to see if pre-surgery treatment can improve outcomes for people with resectable locally advanced head and neck squamous cell carcinoma.

  Recruiting Phase 2 West China Hospital · Chengdu, Sichuan · NCT07381075

• Treatment for metastatic nasopharyngeal carcinoma using a combination of drugs

  This study is testing a new combination of drugs to see if it can help people with advanced nasopharyngeal cancer live longer without their cancer getting worse.

  Recruiting Phase 1 Zhejiang Cancer Hospital · Hangzhou, Zhejiang · NCT06886347

• Treatment for advanced solid tumors using LM-108 and other therapies

  This study is testing a new treatment called LM-108 combined with other cancer therapies to see if it helps people with advanced solid tumors feel better.

  Recruiting at 2 sites Phase 1/2 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Hefei, Anhui and 31 other locations · NCT06825494

• LM-108 with penpulimab plus albumin-bound paclitaxel and gemcitabine for advanced pancreatic cancer (Cohort C)

  This study will test whether adding LM-108 to penpulimab with albumin-bound paclitaxel and gemcitabine helps people with advanced pancreatic cancer.

  Recruiting Phase 1/2 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Beijing, Beijing Municipality and 15 other locations · NCT06821503

• Combining penpulimab, anlotinib, and chemotherapy for esophageal cancer treatment

  This study is testing if a new combination of medications, including penpulimab and anlotinib, can improve treatment for people with advanced esophageal cancer before surgery.

  Recruiting Phase 2 Xijing Hospital · Xi'an, Shaan'xi · NCT06586242

• Combining Anlotinib and Penpulimab for Hepatocellular Carcinoma Treatment

  This study is testing if a new combination of two treatments can help prevent liver cancer from coming back in patients who are at high risk after surgery or other treatments.

  Recruiting at 47 sites Phase 3 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Bengbu, Anhui and 66 other locations · NCT05862337

• Short-course radiotherapy followed by penpulimab plus CAPEOX before surgery for microsatellite-stable locally advanced rectal cancer

  This study tests whether short-course radiotherapy followed by the immunotherapy penpulimab combined with CAPEOX chemotherapy before surgery helps people with microsatellite-stable locally advanced rectal cancer.

  Recruiting Phase 2 Ruijin Hospital · Shanghai, None Selected · NCT05576480

• Combination treatment for ctDNA positive gastric cancer

  This study is testing a new combination treatment for patients with a specific type of stomach cancer to see if it works better than the usual treatment.

  Recruiting Phase 2 The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT05494060

• Combination treatment of Penpulimab and Cetuximab for advanced head and neck cancer

  This study is testing a new combination of two medications, Penpulimab and Cetuximab, to see if they can help people with advanced head and neck cancer who haven't had treatment before.

  Recruiting at 2 sites Phase 2 Eye & ENT Hospital of Fudan University · Changchun, Jilin and 1 other locations · NCT05260671

• Combination of Penpulimab and Chemotherapy for Advanced Esophageal Cancer

  This study is testing if adding Anlotinib to Penpulimab and chemotherapy can help people with advanced esophageal cancer feel better compared to just using Penpulimab and chemotherapy alone.

  Recruiting Phase 2 Nanfang Hospital, Southern Medical University · Guangzhou, Guangdong · NCT05214222

• Preoperative intensity-modulated radiotherapy with concurrent anlotinib for localized extremity and trunk soft tissue sarcoma

  This test combines preoperative IMRT and the drug anlotinib to see if it improves outcomes for adults with primary soft tissue sarcoma of the arms, legs, or trunk.

  Recruiting Phase 2 Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing, Beijing Municipality · NCT05167994

Quick answers

How many clinical trials of Penpulimab are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in China. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 7, Phase 1/2: 2, Phase 1: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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