Drug or treatment

Momelotinib clinical trials

• 6Clinical trials
• 9Countries

Newest trials

All recruiting trials (6)

• Momelotinib given before and after allogeneic bone marrow transplant for myelofibrosis

  This test will see if giving momelotinib around the time of allogeneic hematopoietic cell transplant is safe and tolerable for adults with intermediate- or high-risk myelofibrosis.

  Recruiting Phase 1 Massachusetts General Hospital · Boston, Massachusetts · NCT07104799

• Momelotinib treatment for VEXAS syndrome

  This trial will test whether the oral drug momelotinib helps adults with VEXAS syndrome (with or without myelodysplastic syndrome) who need daily steroids to control inflammation.

  Recruiting at 2 sites Phase 2 Groupe Francophone des Myelodysplasies · Angers and 10 other locations · NCT07098936

• Momelotinib plus azacitidine for chronic-phase MDS/MPN and chronic neutrophilic leukemia

  This trial will test whether adding momelotinib to a standard hypomethylating drug helps adults with chronic-phase MDS/MPN or chronic neutrophilic leukemia control their disease and symptoms.

  Recruiting Early Phase 1 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Baltimore, Maryland · NCT07071155

• Momelotinib for adults with low‑risk myelodysplastic syndrome

  This trial will test if momelotinib can reduce red blood cell transfusion needs and is safe in adults with low‑risk myelodysplastic syndrome who are refractory or intolerant to prior ESA or luspatercept.

  Recruiting at 39 sites Phase 2 GlaxoSmithKline · Goodyear, Arizona and 38 other locations · NCT06847867

• Combining Momelotinib and Luspatercept for Myelofibrosis Treatment

  This study is testing if combining two medications, momelotinib and luspatercept, can help people with myelofibrosis who need blood transfusions feel better and reduce their transfusion needs.

  Recruiting at 33 sites Phase 2 GlaxoSmithKline · Ann Arbor, Michigan and 32 other locations · NCT06517875

• Combining Gilteritinib and Momelotinib for FLT3-Mutated Acute Myeloid Leukemia

  This study is testing a new combination of two drugs, gilteritinib and momelotinib, to see if they can safely help adults with a specific type of leukemia that hasn't responded to other treatments.

  Recruiting Phase 1/2 M.D. Anderson Cancer Center · Houston, Texas · NCT06235801

Quick answers

How many clinical trials of Momelotinib are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (5 trials), France (3 trials), Canada (2 trials), Germany (2 trials), Italy (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1/2: 1, Phase 1: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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