Drug or treatment

Linvoseltamab clinical trials

• 14Clinical trials
• 31Countries

Newest trials

All recruiting trials (14)

• Linvoseltamab with pre-dose Tocilizumab to reduce CRS in adults with relapsed/refractory multiple myeloma

  This study tests whether giving tocilizumab before the first dose of linvoseltamab can lower the risk of cytokine release syndrome in adults with relapsed/refractory multiple myeloma who have had at least four prior therapies.

  Recruiting at 7 sites Phase 4 Regeneron Pharmaceuticals · Los Angeles, California and 6 other locations · NCT07609940

• REGN17372 plus linvoseltamab tolerability for adults with relapsed/refractory multiple myeloma

  This trial tests whether giving REGN17372 together with linvoseltamab is safe and what dose works for adults whose multiple myeloma has come back or stopped responding.

  Recruiting at 9 sites Phase 1/2 Regeneron Pharmaceuticals · Liverpool, New South Wales and 8 other locations · NCT07455851

• Linvoseltamab vs. Daratumumab in high-risk smoldering myeloma

  This study tests whether linvoseltamab can delay progression to active myeloma better than daratumumab in people with high-risk smoldering multiple myeloma.

  Recruiting at 33 sites Phase 3 Regeneron Pharmaceuticals · Phoenix, Arizona and 32 other locations · NCT07393282

• Linvoseltamab alone or with carfilzomib versus standard combination regimens for adults with relapsed/refractory multiple myeloma.

  This trial tests whether linvoseltamab alone or together with carfilzomib works better than standard combination treatments for adults with relapsed or refractory multiple myeloma who have had 1–3 prior therapies.

  Recruiting at 53 sites Phase 3 Regeneron Pharmaceuticals · Atlanta, Georgia and 52 other locations · NCT07222761

• Response-based lowering of linvoseltamab doses for relapsed or refractory multiple myeloma

  This trial tests whether lowering linvoseltamab doses for people with relapsed or refractory multiple myeloma can control the cancer while reducing side effects.

  Recruiting Phase 1/2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT07181941

• Linvoseltamab versus standard daratumumab‑lenalidomide‑dexamethasone for adults with newly diagnosed, transplant‑ineligible multiple myeloma

  This trial tests whether linvoseltamab works better or is safer than the standard daratumumab‑lenalidomide‑dexamethasone combination in adults newly diagnosed with multiple myeloma who are not eligible for transplant.

  Recruiting at 59 sites Phase 3 European Myeloma Network B.V. · Adelaide and 58 other locations · NCT06932562

• Add linvoseltamab to lenalidomide maintenance to deepen responses and regain MRD-negative status in newly diagnosed multiple myeloma

  This trial tests whether adding linvoseltamab to lenalidomide maintenance can clear remaining myeloma cells (make you MRD-negative) or help patients who relapsed get back to MRD-negative in newly diagnosed multiple myeloma.

  Recruiting Phase 2 University of Miami · Miami, Florida · NCT06910124

• Testing REGN7945 with linvoseltamab for relapsed multiple myeloma

  This study is testing a new drug called REGN7945 combined with linvoseltamab to see if it helps adults with relapsed multiple myeloma better than linvoseltamab alone.

  Recruiting at 9 sites Phase 1/2 Regeneron Pharmaceuticals · Sydney, New South Wales and 8 other locations · NCT06669247

• Using Linvoseltamab to treat newly diagnosed multiple myeloma

  This study is testing if a new treatment called Linvoseltamab can help people with newly diagnosed multiple myeloma get rid of leftover cancer cells after their initial therapy.

  Recruiting Phase 2 University of Miami · Miami, Florida · NCT06376526

• Testing linvoseltamab for treating relapsed or refractory AL amyloidosis in adults

  This study is testing a new drug called linvoseltamab to see if it can help adults with relapsed or refractory AL amyloidosis feel better and improve their organ function.

  Recruiting at 20 sites Phase 1/2 Regeneron Pharmaceuticals · Duarte, California and 20 other locations · NCT06292780

• Testing linvoseltamab for eliminating abnormal plasma cells in patients with high-risk MGUS or smoldering multiple myeloma

  This study is testing if a new drug called linvoseltamab can help get rid of abnormal plasma cells in patients with high-risk MGUS or smoldering multiple myeloma.

  Recruiting at 39 sites Phase 2 Regeneron Pharmaceuticals · Baltimore, Maryland and 38 other locations · NCT06140524

• Comparing linvoseltamab to a combination of three other cancer drugs for relapsed/refractory multiple myeloma

  This study is testing if a new drug called linvoseltamab works better than a standard combination of three other cancer drugs for adults with relapsed or refractory multiple myeloma.

  Recruiting at 19 sites Phase 3 Regeneron Pharmaceuticals · Los Angeles, California and 158 other locations · NCT05730036

• Examining the effects of linvoseltamab with other cancer treatments for multiple myeloma

  This study is testing a new drug called linvoseltamab along with other cancer treatments to see how well it works and how safe it is for adults with relapsed or refractory multiple myeloma.

  Recruiting at 42 sites Phase 1 Regeneron Pharmaceuticals · La Jolla, California and 41 other locations · NCT05137054

• Testing REGN5458 for patients with relapsed or refractory multiple myeloma

  This study is testing a new drug called REGN5458 to see if it can safely help adults with relapsed or refractory multiple myeloma who have few treatment options.

  Recruiting at 25 sites Phase 1/2 Regeneron Pharmaceuticals · Miami, Florida and 39 other locations · NCT03761108

Quick answers

How many clinical trials of Linvoseltamab are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 31 countries. The most sites are in United States (11 trials), Spain (6 trials), United Kingdom (6 trials), South Korea (5 trials), Australia (5 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 5, Phase 3: 4, Phase 2: 3, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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