Drug or treatment

Lazertinib clinical trials

• 6Clinical trials
• 18Countries

Newest trials

All recruiting trials (6)

• Lower starting lazertinib dose with magnesium to prevent nerve side effects in EGFR-mutant NSCLC

  This study tests whether starting lazertinib at a lower dose plus magnesium helps prevent peripheral neuropathy in newly diagnosed EGFR-mutant NSCLC patients.

  Recruiting Phase 2 Samsung Medical Center · Seoul, Gang-nam Gu · NCT07774520

• Amivantamab with Lazertinib or Chemotherapy before surgery in EGFR-mutated NSCLC

  This study tests whether giving amivantamab together with lazertinib or with carboplatin and pemetrexed before surgery can slow or stop tumor growth in people with resectable EGFR-mutated NSCLC.

  Recruiting at 27 sites Phase 2 Janssen Research & Development, LLC · Duarte, California and 26 other locations · NCT07586202

• Combining Amivantamab with Lazertinib or Chemotherapy for Advanced Lung Cancer

  This study tests if a new combination of amivantamab with lazertinib or chemotherapy can help people with advanced lung cancer that has certain genetic changes.

  Recruiting at 68 sites Phase 2 Janssen Research & Development, LLC · Daphne, Alabama and 204 other locations · NCT06667076

• Comparing Lazertinib Alone to Lazertinib with Bevacizumab for Lung Cancer in Smokers

  This study is testing whether combining Lazertinib with Bevacizumab can help smokers with advanced lung cancer live longer without their disease getting worse compared to just using Lazertinib alone.

  Recruiting Phase 2 National Cancer Center, Korea · Suwon, Gyeonggi-do and 4 other locations · NCT06156527

• Adding tepotinib to lazertinib for EGFR‑mutant metastatic lung cancer with MET overexpression or amplification after progression on lazertinib

  This trial tests whether adding the MET blocker tepotinib to lazertinib helps people with EGFR‑mutant metastatic non‑small cell lung cancer whose tumors show MET overexpression or amplification and who have progressed on lazertinib.

  Recruiting Phase 2 Samsung Medical Center · Seoul, Gangnam-gu · NCT06106802

• Neoadjuvant treatment with lazertinib for lung cancer patients with specific mutations

  This study is testing if a new lung cancer treatment called lazertinib can help patients with specific mutations feel better and reduce the chances of their cancer coming back after surgery.

  Recruiting Phase 2 Konkuk University Medical Center · Seoul · NCT05469022

Quick answers

How many clinical trials of Lazertinib are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 18 countries. The most sites are in South Korea (5 trials), Spain (2 trials), United States (2 trials), Belgium (1 trial), Finland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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