Drug or treatment

Izalontamab clinical trials

• 5Clinical trials
• 33Countries

Newest trials

All recruiting trials (5)

• Izalontamab Brengitecan with Osimertinib in EGFR-mutant NSCLC: first-line versus standard options

  This study tests whether adding iza-bren to osimertinib can help people with newly diagnosed EGFR-mutant non-small cell lung cancer, compared with osimertinib alone or osimertinib plus platinum-based chemotherapy.

  Recruiting at 10 sites Phase 3 Bristol-Myers Squibb · Beverly Hills, California and 204 other locations · NCT07680790

• Izalontamab Brengitecan plus Adagrasib in KRAS G12C NSCLC

  This study tests whether the drug combo iza-bren and adagrasib can help adults with advanced KRAS G12C-mutant non-small cell lung cancer that has progressed after KRAS G12C inhibitors fail.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT07382726

• Izalontamab Brengitecan versus Platinum Chemotherapy for Advanced Urothelial Cancer

  This trial tests whether izalontamab brengitecan works better than standard platinum-based chemotherapy for people with metastatic urothelial (bladder) cancer that progressed after prior immunotherapy.

  Recruiting at 122 sites Phase 2/3 Bristol-Myers Squibb · Gilbert, Arizona and 162 other locations · NCT07106762

• Izalontamab brengitecan versus platinum-pemetrexed for EGFR‑mutated non‑small cell lung cancer after EGFR TKI failure

  This trial tests whether izalontamab brengitecan works better than platinum‑pemetrexed chemotherapy for people with EGFR‑mutated non‑small cell lung cancer that has progressed after third‑generation EGFR TKI treatment.

  Recruiting at 45 sites Phase 2/3 Bristol-Myers Squibb · Irvine, California and 186 other locations · NCT07100080

• Evaluating BMS-986504 for advanced lung cancer with specific genetic deletion

  This study is testing a new drug called BMS-986504 to see if it can help people with advanced lung cancer who have a specific genetic change and have not responded to previous treatments.

  Recruiting at 65 sites Phase 2 Bristol-Myers Squibb · Anchorage, Alaska and 66 other locations · NCT06855771

Quick answers

How many clinical trials of Izalontamab are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 33 countries. The most sites are in United States (5 trials), China (4 trials), France (4 trials), Germany (4 trials), Italy (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 2, Phase 3: 1, Phase 2: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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