Drug or treatment

Ifinatamab clinical trials

• 9Clinical trials
• 43Countries

Newest trials

All recruiting trials (9)

• Ifinatamab Deruxtecan in kids with relapsed or refractory solid cancers

  This study tests whether I-DXd can help children whose solid tumors have come back or not responded to previous treatments.

  Recruiting at 35 sites Phase 1/2 Merck Sharp & Dohme LLC · Los Angeles, California and 34 other locations · NCT07630974

• Ifinatamab deruxtecan for advanced esophageal squamous cell carcinoma

  This trial will test whether ifinatamab deruxtecan can shrink or eliminate advanced esophageal squamous cell carcinoma in people whose cancer progressed after one or two prior systemic treatments.

  Recruiting at 34 sites Phase 1/2 Merck Sharp & Dohme LLC · Pittsburgh, Pennsylvania and 33 other locations · NCT07405151

• Gocatamig and ifinatamab deruxtecan combined with standard therapy for extensive-stage small cell lung cancer

  This trial tests whether giving gocatamig and ifinatamab deruxtecan, alone or with standard chemotherapy plus immunotherapy, helps people with extensive-stage small cell lung cancer.

  Recruiting at 58 sites Phase 1/2 Merck Sharp & Dohme LLC · Santa Rosa, California and 57 other locations · NCT07227597

• New treatment for metastatic prostate cancer using ifinatamab deruxtecan

  This study is testing a new treatment called ifinatamab deruxtecan to see if it helps men with advanced prostate cancer live longer and feel better compared to standard chemotherapy.

  Recruiting at 290 sites Phase 3 Merck Sharp & Dohme LLC · Phoenix, Arizona and 302 other locations · NCT06925737

• Ifinatamab deruxtecan alone or with other drugs for metastatic castration‑resistant prostate cancer

  This trial tests whether ifinatamab deruxtecan, given alone or with other cancer drugs, helps men with metastatic castration‑resistant prostate cancer by lowering PSA and controlling disease.

  Recruiting at 80 sites Phase 1/2 Merck Sharp & Dohme LLC · Los Angeles, California and 81 other locations · NCT06863272

• Evaluating new treatments for relapsed small cell lung cancer

  This study is testing two new drugs to see if they can help people with advanced small cell lung cancer that hasn't responded to other treatments.

  Recruiting at 44 sites Phase 1/2 Merck Sharp & Dohme LLC · Aurora, Colorado and 47 other locations · NCT06780137

• Evaluating ifinatamab deruxtecan for advanced esophageal cancer

  This study is testing a new drug called ifinatamab deruxtecan to see if it helps people with advanced esophageal cancer who haven't responded to other treatments live longer and feel better compared to those getting standard chemotherapy.

  Recruiting at 167 sites Phase 3 Daiichi Sankyo · Phoenix, Arizona and 167 other locations · NCT06644781

• Evaluating a new treatment for extensive stage-small cell lung cancer

  This study is testing a new treatment combining ifinatamab deruxtecan and atezolizumab, with or without carboplatin, to see if it can help people with extensive stage-small cell lung cancer feel better and improve their treatment results.

  Recruiting at 55 sites Phase 1/2 Daiichi Sankyo · Birmingham, Alabama and 57 other locations · NCT06362252

• Evaluating Ifinatamab Deruxtecan for Recurrent or Metastatic Solid Tumors

  This study is testing a new drug called ifinatamab deruxtecan to see if it can help people with recurrent or metastatic solid tumors that have already been treated.

  Recruiting at 104 sites Phase 1/2 Daiichi Sankyo · Los Angeles, California and 119 other locations · NCT06330064

Quick answers

How many clinical trials of Ifinatamab are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 43 countries. The most sites are in Spain (8 trials), United States (8 trials), South Korea (7 trials), France (7 trials), Chile (6 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 7, Phase 3: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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