Drug or treatment

Envafolimab clinical trials

• 18Clinical trials
• 4Countries

Newest trials

All recruiting trials (18)

• First-line chemo with hepatic arterial infusion plus Envafolimab and Lenvatinib for unresectable biliary tract cancer

  This trial tests a first-line treatment combining hepatic arterial infusion chemotherapy with Envafolimab and Lenvatinib to see if it helps patients with unresectable biliary tract cancer.

  Recruiting Phase 1/2 West China Hospital · Chengdu, Sichuan · NCT07636798

• Envafolimab in real-world use for advanced solid tumors

  This study looks at real-world safety and effectiveness of Envafolimab given as a patient-access program for adults with advanced solid tumors.

  Recruiting Ir Innovate Research Private Limited · Nairobi and 3 other locations · NCT07562347

• Regorafenib plus envafolimab versus physician's choice for metastatic GIST with KIT exon 17 mutation

  This study will test whether combining regorafenib with the immune drug envafolimab helps people with metastatic GIST who have KIT exon 17 mutations and have stopped responding to standard treatments.

  Recruiting Phase 2 Peking University Cancer Hospital & Institute · Beijing, Beijing Municipality · NCT07559864

• Envafolimab with albumin-bound paclitaxel and carboplatin before surgery for resectable locally advanced esophageal squamous cell carcinoma

  This study tests whether adding envafolimab to albumin-bound paclitaxel and carboplatin before surgery helps people with resectable locally advanced esophageal squamous cell carcinoma.

  Recruiting Phase 2 Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT07266493

• KGX101 alone and with envafolimab for advanced or metastatic solid tumors

  This trial will test whether KGX101 by itself or combined with envafolimab is safe and tolerable for adults in China with advanced or metastatic solid tumors.

  Recruiting at 3 sites Phase 1 Kangabio AUSTRALIA LTD PTY · Beijing, Beijing Municipality and 2 other locations · NCT07260305

• Neoadjuvant treatment for gastric cancer using Envafolimab and Fruquintinib with chemotherapy

  This study is testing if a new combination of Envafolimab, Fruquintinib, and chemotherapy can help people with locally advanced gastric cancer do better before surgery.

  Recruiting Phase 2 First Affiliated Hospital of Fujian Medical University · Fuzhou, Fujian · NCT06791083

• Combination treatment for resectable HER2-mutant non-small cell lung cancer

  This study is testing a new combination treatment for people with resectable HER2-mutant non-small cell lung cancer to see if it can improve their chances of recovery after surgery.

  Recruiting Phase 2 Guangdong Provincial People's Hospital · Guangzhou · NCT06734182

• Combination therapy for extensive-stage small cell lung cancer

  This study is testing a new combination of medications to see if it can help people with extensive-stage small cell lung cancer feel better and improve their treatment outcomes.

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06698965

• Combining D-TACE-HAIC with Envafolimab and Lenvatinib for treating advanced liver cancer

  This study is testing a new treatment combining D-TACE-HAIC, Envafolimab, and Lenvatinib to see if it helps people with advanced liver cancer that can't be surgically removed.

  Recruiting Fujian Provincial Hospital · Fuzhou, Fujian · NCT06643208

• Combining Donafenib and Envafolimab for Patients at High Risk of Liver Cancer Recurrence

  This study is testing if a new combination of two drugs, donafenib and envafolimab, can help prevent liver cancer from coming back in patients who have just had surgery for it and are at high risk for recurrence.

  Recruiting at 2 sites Phase 2 Anhui Provincial Hospital · Fuyang, Anhui and 1 other locations · NCT06498622

• Combination treatment for metastatic colorectal cancer

  This study is testing a combination of three drugs to see if it can help patients with certain types of metastatic colorectal cancer who have previously responded well to similar treatments.

  Recruiting Phase 2 Beijing Hospital · Beijing, Beijing Municipality · NCT06321081

• Envafolimab with chemotherapy for resectable stage III lung cancer

  This study is testing if adding a new drug called envafolimab to standard chemotherapy can help people with resectable stage III lung cancer do better before and after surgery.

  Recruiting Phase 3 3D Medicines · Tianjin, Tianjin Municipality · NCT06123754

• Combining envafolimab with chemoradiotherapy for advanced nasopharyngeal carcinoma

  This study is testing if adding a new drug called envafolimab to standard chemotherapy and radiation can help people with advanced nasopharyngeal cancer do better in their treatment.

  Recruiting Phase 2 Chongqing University Cancer Hospital · Chongqing, Chongqing Municipality · NCT06059261

• New treatment combination for advanced left-side colorectal cancer

  This study is testing a new combination of treatments for people with advanced left-side colorectal cancer to see if it helps them live longer without the cancer getting worse compared to the standard treatment.

  Recruiting at 3 sites Phase 2 Sun Yat-sen University · Foshan, Guangdong and 2 other locations · NCT05959356

• Combining Envafolimab with Chemoradiotherapy for Advanced Nasopharyngeal Cancer

  This study is testing if combining a new drug called Envafolimab with standard chemotherapy and radiation can help people with advanced nasopharyngeal cancer live longer without their cancer getting worse.

  Recruiting Phase 2 Sun Yat-sen University · Guangzhou, Guangdong · NCT05397769

• Treatment of advanced endometrial cancer with Envafolimab and Lenvatinib

  This study is testing if a new treatment combining Envafolimab and Lenvatinib can help people with advanced endometrial cancer who haven't had success with regular chemotherapy.

  Recruiting at 19 sites Phase 2 3D Medicines · Beijing, Beijing Municipality and 18 other locations · NCT05112991

• Combining Envafolimab and Lenvatinib for treating advanced solid tumors

  This study is testing if combining two drugs, Envafolimab and Lenvatinib, can help people with advanced solid tumors feel better when other treatments haven't worked.

  Recruiting at 16 sites Phase 1/2 3D Medicines · Bengbu, Anhui and 22 other locations · NCT05024214

• Treatment with Envafolimab for advanced solid tumors

  This study is testing if a new treatment called Envafolimab can help people with advanced solid tumors, especially looking at how well it works for those with high versus low tumor mutation levels.

  Recruiting Phase 2 3D Medicines · Beijing · NCT04891198

Quick answers

How many clinical trials of Envafolimab are recruiting right now?

18, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in China (17 trials), Kenya (1 trial), Mauritius (1 trial), Philippines (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 12, Phase 1/2: 2, Phase 1: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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