Condition

Von Willebrand Disease (VWD) clinical trials and research

• 10Clinical trials
• 16Countries

Newest Von Willebrand Disease (VWD) clinical trials

All recruiting trials (10)

• SR604 in Von Willebrand Disease: a Phase II study to see if it helps with bleeding

  This Phase 2 trial tests SR604 in adults with von Willebrand disease to see if it can improve bleeding control and how the drug behaves in the body.

  Recruiting at 9 sites Phase 2 Shanghai RAAS Blood Products Co., Ltd. · Changsha and 8 other locations · NCT07640893

• ALN-6400 for women with von Willebrand disease and heavy menstrual bleeding

  This study tests ALN-6400 to see if it can help reduce heavy menstrual bleeding in adult and adolescent women with von Willebrand disease.

  Recruiting Phase 2 Alnylam Pharmaceuticals · Orange, California and 20 other locations · NCT07575308

• Vonicog alfa (rVWF) use in children with von Willebrand disease

  This observational program will see how vonicog alfa (rVWF) works and whether it causes side effects in children with von Willebrand disease in Japan.

  Recruiting Takeda · Tokyo, Tokyo · NCT07404644

• Endothelial colony-forming cell behavior in people with von Willebrand disease and acquired von Willebrand syndrome

  This project will see how endothelial colony-forming cells (ECFCs) behave in people with VWD or AVWS compared with healthy volunteers.

  Recruiting Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · Milan · NCT07358013

• VONVENDI treatment for adults in China with von Willebrand disease

  We will test whether VONVENDI is safe and helps control bleeding in adult Chinese patients with severe von Willebrand disease, sometimes given with ADVATE if their factor VIII is low.

  Recruiting at 7 sites Phase 3 Takeda · Beijing and 6 other locations · NCT07129343

• Subcutaneous VGA039 to prevent bleeds in people with von Willebrand disease

  This study will test whether subcutaneous VGA039 can reduce bleeding in people aged 12–75 with any type of von Willebrand disease who have frequent bleeds.

  Recruiting at 32 sites Phase 3 Vega Therapeutics, Inc · Little Rock, Arkansas and 31 other locations · NCT07115004

• Assessing HMB-002 for treating Von Willebrand Disease

  This study is testing a new treatment called HMB-002 to see if it is safe and effective for adults with Type 1 Von Willebrand Disease.

  Recruiting at 6 sites Phase 1/2 Hemab ApS · Phoenix, Arizona and 24 other locations · NCT06754852

• Algorithm-based management to reduce GI bleeding and epistaxis in von Willebrand disease

  This study tests whether an algorithm-guided, multidisciplinary management approach can cut back GI bleeding and severe nosebleeds in adults with von Willebrand disease compared with standard care.

  Recruiting University Hospital, Lille · Lille, Nord and 16 other locations · NCT06651255

• Understanding bleeding and treatment in Von Willebrand Disease

  This study is trying to learn more about bleeding and treatment experiences in people with Von Willebrand Disease, especially those with Type 1, to help improve future care.

  Recruiting at 17 sites Hemab ApS · Phoenix, Arizona and 16 other locations · NCT06610201

• Evaluating vonicog alfa for children with severe Von Willebrand Disease

  This study is testing a new treatment called vonicog alfa to see if it can help children with severe Von Willebrand Disease manage their bleeding better.

  Recruiting at 19 sites Phase 3 Takeda · Birmingham, Alabama and 22 other locations · NCT05582993

Related topics

Quick answers

How many Von Willebrand Disease (VWD) clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in United Kingdom (5 trials), United States (5 trials), Australia (3 trials), Italy (3 trials), Ireland (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 3, Phase 2: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →