Condition
Stage 4 NSCLC clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Stage 4 NSCLC clinical trials that are recruiting, at sites in 11 countries (most in United States (3), Australia (1), Austria (1)). By phase: Phase 2 (2), Phase 2/3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 11Countries
Newest Stage 4 NSCLC clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Universal immunization to boost immunotherapy response in advanced NSCLC | Phase 2 | Gainesville, Florida | Recruiting | May 19, 2026 |
| EIK1001 with pembrolizumab and chemotherapy in stage 4 non-small cell lung cancer | Phase 2/3 | Daphne, Alabama and 41 other locations | Recruiting | Jan 26, 2026 |
| Radiation therapy for high-risk metastatic lung cancer patients | Phase 2 | Rochester, New York | Recruiting | Feb 16, 2024 |
All recruiting trials (3)
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Universal immunization to boost immunotherapy response in advanced NSCLC
This study tests whether giving the Pfizer COVID-19 mRNA vaccine in combination with frontline pembrolizumab and chemotherapy helps more patients with stage IV NSCLC respond to treatment.
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EIK1001 with pembrolizumab and chemotherapy in stage 4 non-small cell lung cancer
This study tests whether adding EIK1001 to pembrolizumab plus standard chemotherapy can help people with stage 4 NSCLC.
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Radiation therapy for high-risk metastatic lung cancer patients
This study is testing if adding radiation therapy to standard treatment can help high-risk lung cancer patients feel better and slow down their disease.
Related topics
Quick answers
How many Stage 4 NSCLC clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 11 countries. The most sites are in United States (3 trials), Australia (1 trial), Austria (1 trial), Belgium (1 trial), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.