Condition
Smallpox clinical trials and research
As of November 12, 2026, Find a Trial lists 2 Smallpox clinical trials that are recruiting, at sites in 3 countries (most in China (1), Democratic Republic of the Congo (1), South Africa (1)). By phase: Phase 1 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 2Clinical trials
- 3Countries
All recruiting trials (2)
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mRNA vaccine (BNT166a) for mpox and smallpox prevention in adults in Africa
This tests whether two doses of the mRNA vaccine BNT166a are safe and produce an immune response in healthy adults in Africa, including people who have or have not had prior smallpox or mpox exposure.
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Safety, tolerability, and how the body processes BSY001 after single and multiple doses
This trial will test whether BSY001 is safe, well tolerated, and how it is absorbed and cleared when given once or multiple times to healthy adults aged 18–50.
Related topics
Quick answers
How many Smallpox clinical trials are recruiting right now?
2, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in China (1 trial), Democratic Republic of the Congo (1 trial), South Africa (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.