Condition

Refractory Primary Mediastinal Large B-Cell Lymphoma clinical trials and research

• 5Clinical trials
• 2Countries

Newest Refractory Primary Mediastinal Large B-Cell Lymphoma clinical trials

All recruiting trials (5)

• Epcoritamab plus R-GemOx before autologous stem cell transplant for relapsed or refractory DLBCL

  This phase II trial tests whether adding epcoritamab to rituximab with gemcitabine and oxaliplatin (R-GemOx) can help adults with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) achieve remission and proceed to autologous stem cell transplant.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California and 2 other locations · NCT07365306

• Using golcadomide and rituximab to prepare patients for CAR T-cell therapy in aggressive B-cell lymphoma

  This study is testing if a combination of golcadomide and rituximab can help patients with aggressive B-cell lymphoma get ready for CAR T-cell therapy.

  Recruiting at 7 sites Phase 2 Mayo Clinic · Scottsdale, Arizona and 6 other locations · NCT06834373

• Odronextamab as bridging therapy for relapsed or refractory large B‑cell lymphoma before CAR‑T

  This trial tests whether giving odronextamab before CAR‑T cell therapy can keep disease under control in adults with relapsed or refractory large B‑cell lymphomas.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT06784726

• Combination treatment of epcoritamab and ibrutinib for aggressive B-cell lymphoma

  This study is testing a new combination of two treatments, epcoritamab and ibrutinib, to see if they can help people with aggressive B-cell lymphoma that hasn't responded to other therapies.

  Recruiting at 3 sites Phase 1/2 Ohio State University Comprehensive Cancer Center · Minneapolis, Minnesota and 2 other locations · NCT06536049

• Golcadomide treatment after CAR T-cell therapy for aggressive large B-cell lymphoma

  This study is testing if golcadomide can help people with aggressive large B-cell lymphoma stay in remission after they receive CAR T-cell therapy.

  Recruiting at 13 sites Phase 2 The Lymphoma Academic Research Organisation · Créteil and 12 other locations · NCT06271057

Related topics

Quick answers

How many Refractory Primary Mediastinal Large B-Cell Lymphoma clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (4 trials), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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