Condition

Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements clinical trials and research

• 5Clinical trials
• 1Country

Newest Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements clinical trials

All recruiting trials (5)

• Fecal transplant to restore gut microbiome before CAR T therapy for relapsed or refractory B‑cell lymphoma

  This trial will test whether a fecal microbiome transplant can restore healthy gut bacteria and improve outcomes for adults with relapsed or refractory CD19 B‑cell lymphoma who received high‑risk antibiotics and are receiving CAR T‑cell therapy.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT07042438

• ViPOR combination therapy for relapsed or refractory aggressive B‑cell lymphoma

  This treatment will try a five‑drug targeted combination called ViPOR (venetoclax, ibrutinib, prednisone, obinutuzumab, and lenalidomide) in adults whose aggressive B‑cell lymphoma has relapsed or not responded to prior therapy, focusing on specific genetic subtypes like CD10‑negative DLBCL and high‑grade B‑cell lympho

  Recruiting at 99 sites Phase 2 National Cancer Institute (NCI) · Tucson, Arizona and 114 other locations · NCT06649812

• Combination treatment of epcoritamab and ibrutinib for aggressive B-cell lymphoma

  This study is testing a new combination of two treatments, epcoritamab and ibrutinib, to see if they can help people with aggressive B-cell lymphoma that hasn't responded to other therapies.

  Recruiting at 3 sites Phase 1/2 Ohio State University Comprehensive Cancer Center · Minneapolis, Minnesota and 2 other locations · NCT06536049

• Tegavivint treatment for patients with relapsed or refractory large B-cell lymphoma

  This study is testing a new treatment called tegavivint to see if it can help people with relapsed or refractory large B-cell lymphoma feel better and how much of the drug is safe to use.

  Recruiting Phase 1 Ohio State University Comprehensive Cancer Center · Columbus, Ohio · NCT05755087

• Combination chemotherapy for relapsed or refractory acute lymphoblastic leukemia and related conditions

  This study is testing a new combination of chemotherapy drugs to see if it can help people with relapsed or hard-to-treat acute lymphoblastic leukemia and related blood cancers feel better and live longer.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT03136146

Related topics

Quick answers

How many Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1/2: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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