Condition

Refractory Chronic Myelomonocytic Leukemia clinical trials and research

• 9Clinical trials
• 1Country

Newest Refractory Chronic Myelomonocytic Leukemia clinical trials

All recruiting trials (9)

• Testing STX-0712 in patients with advanced blood cancers

  This study is testing a new drug called STX-0712 to see if it can help people with advanced blood cancers like chronic myelomonocytic leukemia and acute myeloid leukemia who have run out of other treatment options.

  Recruiting at 6 sites Phase 1 Solu Therapeutics, Inc · Stanford, California and 6 other locations · NCT06950034

• Decitabine plus FLAG‑Ida chemotherapy and total‑body irradiation before donor stem cell transplant for adults with high‑risk myeloid cancers

  This test tries whether adding decitabine to FLAG‑Ida chemotherapy and total‑body irradiation before a donor stem cell transplant helps adults with high‑risk or relapsed myeloid blood cancers live longer and stay in remission.

  Recruiting Phase 1/2 Fred Hutchinson Cancer Center · Seattle, Washington · NCT06928662

• Q702 to treat blood cancers

  This Phase 1 trial will test whether the oral drug Q702 is safe, tolerable, and what dose works best for adults with certain blood cancers who have failed or are not eligible for standard treatments.

  Recruiting at 2 sites Phase 1 Mayo Clinic · Scottsdale, Arizona and 1 other locations · NCT06712810

• Axatilimab with or without azacitidine for adults with advanced myeloproliferative neoplasms or high‑risk CMML

  This trial tests whether the antibody axatilimab, alone or together with the chemotherapy azacitidine, can help adults with advanced‑phase myeloproliferative neoplasms, MPN/MDS overlap, or high‑risk chronic myelomonocytic leukemia (CMML).

  Recruiting at 2 sites Phase 1/2 Ohio State University Comprehensive Cancer Center · Columbus, Ohio and 1 other locations · NCT06523556

• Onvansertib treatment for recurrent or refractory chronic myelomonocytic leukemia and related conditions

  This study is testing a new drug called onvansertib to see if it can help people with recurring chronic myelomonocytic leukemia and related blood disorders feel better and respond to treatment.

  Recruiting Phase 1 Mayo Clinic · Rochester, Minnesota · NCT05549661

• Chemotherapy and Stem Cell Transplant for Relapsed or Refractory Blood Cancers

  This study is testing a combination of two chemotherapy treatments and total body radiation to see if it helps people with relapsed or hard-to-treat blood cancers get ready for a stem cell transplant.

  Recruiting Phase 1 Fred Hutchinson Cancer Center · Seattle, Washington · NCT04375631

• Treatment of low or intermediate-risk myelodysplastic syndromes and chronic myelomonocytic leukemia with canakinumab

  This study is testing if a new medication called canakinumab can help people with low or intermediate-risk myelodysplastic syndromes and chronic myelomonocytic leukemia feel better and reduce their need for blood transfusions.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT04239157

• Combining azacitidine, venetoclax, and gilteritinib for treating FLT3-mutated blood cancers

  This study is testing a new combination of three medications to see if they can help people with certain types of blood cancers that have a specific genetic mutation.

  Recruiting Phase 1/2 M.D. Anderson Cancer Center · Houston, Texas · NCT04140487

• Using CPX-351 to treat patients with high-risk blood cancers

  This study is testing a new treatment called CPX-351 to see if it can safely help people with high-risk blood cancers like myelodysplastic syndrome or chronic myelomonocytic leukemia.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT03896269

Related topics

Quick answers

How many Refractory Chronic Myelomonocytic Leukemia clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 5, Phase 1/2: 3, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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