Condition
Refractory Angina clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Refractory Angina clinical trials that are recruiting, at sites in 5 countries (most in United Kingdom (2), United States (2), Germany (1)). By phase: Phase 2 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 5Countries
Newest Refractory Angina clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| XC001 delivered by a heart catheter for chronic refractory angina | Phase 2 | Birmingham, Alabama and 13 other locations | Recruiting | Jul 2, 2025 |
| Using stem cells to treat patients with severe angina | Phase 2 | London, England | Recruiting | Feb 3, 2023 |
| Treatment for patients with severe chest pain not relieved by medication | — | Phoenix, Arizona and 96 other locations | Recruiting | Nov 1, 2021 |
| Coronary Sinus Reducer for treating refractory microvascular angina | — | Mainz, Rhineland-Palatinate | Recruiting | Oct 28, 2020 |
| Implanting a device to treat severe angina in patients who can't undergo surgery | — | Tel Aviv and 1 other locations | Recruiting | Mar 29, 2012 |
All recruiting trials (5)
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XC001 delivered by a heart catheter for chronic refractory angina
This trial will try XC001 delivered through a catheter into the heart to reduce angina symptoms in adults 18–85 with refractory angina from blocked coronary arteries who cannot have bypass surgery or stents.
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Using stem cells to treat patients with severe angina
This study is testing whether using stem cells from patients' own bone marrow can help people with severe angina feel better and improve their quality of life.
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Treatment for patients with severe chest pain not relieved by medication
This study is testing a new device called the Shockwave Reducer to see if it can help people with severe chest pain that doesn't get better with regular medications.
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Coronary Sinus Reducer for treating refractory microvascular angina
This study is testing whether a device called the Coronary Sinus Reducer can help people with severe chest pain from microvascular angina feel better when combined with their usual heart medications.
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Implanting a device to treat severe angina in patients who can't undergo surgery
This study is testing a new device to see if it can help people with severe chest pain who can't have surgery feel better and improve their quality of life.
Related topics
Quick answers
How many Refractory Angina clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 5 countries. The most sites are in United Kingdom (2 trials), United States (2 trials), Germany (1 trial), Israel (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.