Condition

Pulmonary Disease, Chronic Obstructive clinical trials and research

• 16Clinical trials
• 1New in 30 days
• 39Countries

Newest Pulmonary Disease, Chronic Obstructive clinical trials

All recruiting trials (16)

• Ensa?fentrine to help prevent COPD flare-ups in adults on standard care

  This study tests whether ensifentrine (MK-5884) can help prevent moderate or severe COPD exacerbations compared with placebo in adults already receiving standard COPD treatment.

  Recruiting at 7 sites Phase 3 Merck Sharp & Dohme LLC · Hialeah Gardens, Florida and 6 other locations · NCT07874815

• GSK Investigational Medicine GSK3862995B: two formulations in healthy adults

  This early-phase study tests two formulations of GSK3862995B in healthy adults to see how the body handles the drug and whether it is safe and tolerable.

  Recruiting Phase 1 GlaxoSmithKline · Cambridge · NCT07789899

• GSK5784283 added to standard COPD therapy vs placebo in moderate to very severe COPD

  This study tests whether adding GSK5784283 to current COPD treatment reduces the rate of COPD flare-ups in adults with eosinophilic COPD and a history of exacerbations.

  Recruiting at 7 sites Phase 3 GlaxoSmithKline · Doral, Florida and 6 other locations · NCT07780669

• GSK5784283 added to standard COPD care versus placebo in adults with moderate to very severe COPD

  This study tests whether adding GSK5784283 to a patient’s current COPD treatment helps reduce COPD flare-ups compared with a placebo in adults with eosinophilic COPD and a history of frequent exacerbations.

  Recruiting at 8 sites Phase 3 GlaxoSmithKline · Cape Coral, Florida and 7 other locations · NCT07780656

• Brenipatide for adults with moderate-to-severe COPD

  This study tests different doses of Brenipatide to see if it is safe and effective for adults with moderate-to-severe COPD, compared with placebo.

  Recruiting at 69 sites Phase 2 Eli Lilly and Company · Birmingham, Alabama and 126 other locations · NCT07759245

• Early depemokimab treatment for COPD with type 2 (eosinophilic) inflammation

  This trial will test whether adding depemokimab early to standard care helps adults with moderate-to-severe COPD who have type 2 (eosinophilic) inflammation.

  Recruiting at 121 sites Phase 3 GlaxoSmithKline · Newport Beach, California and 120 other locations · NCT07177339

• Depemokimab for adults with COPD and eosinophilic (type 2) inflammation

  This study will test whether adding depemokimab to usual inhaled therapy can reduce flare-ups and improve outcomes for adults (40–80) with moderate-to-severe COPD and high blood eosinophils.

  Recruiting at 193 sites Phase 3 GlaxoSmithKline · Sheffield, Alabama and 192 other locations · NCT06961214

• Depemokimab — a long‑acting biologic for adults with COPD and type 2 inflammation.

  This trial will test whether adding depemokimab, a long‑acting injectable biologic, reduces flare-ups and improves symptoms in adults with uncontrolled moderate-to-severe COPD who have type 2 inflammation.

  Recruiting at 281 sites Phase 3 GlaxoSmithKline · Bakersfield, California and 280 other locations · NCT06959095

• Monitoring oxygen therapy usage in COPD patients

  This study is testing a new device that tracks how well COPD patients are using their oxygen therapy to help them breathe better and stay healthier.

  Recruiting University of Virginia · Charlottesville, Virginia · NCT06810323

• Epithelial repair in COPD using patient-derived iPS cells

  This will try using each patient's own iPS cells to repair damaged bronchial lining in people with COPD, smokers without COPD, and non-smoking controls.

  Recruiting University Hospital, Montpellier · Montpellier, Hérault · NCT06755008

• Walking on downhill, level, or uphill treadmill slopes to improve balance in COPD

  This study will test whether 8 weeks of twice-weekly treadmill walking on downhill, level, or uphill slopes helps improve balance in people with COPD.

  Recruiting Acibadem University · Istanbul, Eyüp Sultan · NCT06644898

• Walking on level, uphill, or downhill slopes for people with COPD

  This project will try treadmill walking on level, uphill, and downhill slopes twice a week for eight weeks to see if one type helps people with COPD walk farther and breathe better.

  Recruiting Acibadem University · Istanbul, Eyüp Sultan · NCT06283004

• Reducing hospital admissions for COPD patients using home nursing interventions

  This study tests if home nursing support and education can help people with severe COPD stay healthier and avoid going back to the hospital.

  Recruiting Necmettin Erbakan University · Konya · NCT05730088

• Monitoring end-tidal carbon dioxide levels in COPD exacerbations

  This study is testing if measuring carbon dioxide levels in the breath can help doctors figure out how severe a COPD flare-up is for patients coming to the emergency room.

  Recruiting at 2 sites University Hospital, Grenoble · Grenoble, Isère and 1 other locations · NCT05704881

• Determining the best aspirin dose for COPD patients

  This study is testing whether different doses of aspirin can help people with COPD breathe better and feel more comfortable.

  Recruiting Phase 3 Johns Hopkins University · Baltimore, Maryland · NCT05265299

• Cohort study on COPD exacerbations in London

  This study looks at what causes flare-ups in people with COPD to help understand how the disease affects their health.

  Recruiting Imperial College London · London · NCT02755974

Related topics

Quick answers

How many Pulmonary Disease, Chronic Obstructive clinical trials are recruiting right now?

16, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 39 countries. The most sites are in United States (9 trials), United Kingdom (5 trials), Germany (4 trials), Japan (4 trials), France (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 7, Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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