Condition
Progressive Multiple Sclerosis clinical trials and research
Research outlook What's coming for Multiple sclerosis: the next 6 months to 5 yearsAs of November 12, 2026, Find a Trial lists 4 Progressive Multiple Sclerosis clinical trials that are recruiting, at sites in 14 countries (most in Spain (2), United Kingdom (2), United States (2)). By phase: Phase 2 (2), Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 14Countries
Newest Progressive Multiple Sclerosis clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Virtual nature walks for depression in progressive multiple sclerosis | — | Ann Arbor, Michigan | Recruiting | Feb 6, 2026 |
| Adding RO7268489 to ocrelizumab for progressive multiple sclerosis | Phase 2 | Camperdown, New South Wales and 113 other locations | Recruiting | Dec 15, 2025 |
| Obe-cel for refractory progressive multiple sclerosis | Phase 1 | Palo Alto, California and 6 other locations | Recruiting | Aug 24, 2025 |
| Nicotinamide riboside for treating progressive multiple sclerosis | Phase 2 | Bergen | Recruiting | Feb 23, 2023 |
All recruiting trials (4)
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Virtual nature walks for depression in progressive multiple sclerosis
This project tests whether immersive at-home virtual-reality nature walks using the Apple Vision Pro, added to usual care, can reduce depressive symptoms in people with progressive MS.
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Adding RO7268489 to ocrelizumab for progressive multiple sclerosis
This trial will test whether adding RO7268489 to ocrelizumab helps adults with progressive multiple sclerosis.
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Obe-cel for refractory progressive multiple sclerosis
This trial will test whether a single infusion of obe-cel, a CD19-directed CAR‑T therapy, is safe and shows early benefit in adults 18–60 with progressive MS that has not responded to prior high-efficacy treatments.
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Nicotinamide riboside for treating progressive multiple sclerosis
This study is testing if a supplement called Nicotinamide riboside can help people with progressive multiple sclerosis slow down their disability over 30 months.
Related topics
Quick answers
How many Progressive Multiple Sclerosis clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 14 countries. The most sites are in Spain (2 trials), United Kingdom (2 trials), United States (2 trials), Australia (1 trial), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.