Condition
Progressive Multifocal Leukoencephalopathy clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Progressive Multifocal Leukoencephalopathy clinical trials that are recruiting, at sites in 2 countries (most in United States (4), China (1)). By phase: Phase 1 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 2Countries
Newest Progressive Multifocal Leukoencephalopathy clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| PML risk in people with MS treated with ozanimod | — | Lawrenceville, New Jersey | Recruiting | Jul 29, 2026 |
| Observational cohort of chronic brain viral infections (including PML) | — | Beijing, Beijing Municipality | Recruiting | Apr 6, 2026 |
| Intravenous brincidofovir treatment for progressive multifocal leukoencephalopathy | Phase 2 | Bethesda, Maryland | Recruiting | Apr 6, 2026 |
| Using a radioactive tracer to detect immune cells in the brain for multiple sclerosis and PML | Phase 1 | Bethesda, Maryland | Recruiting | May 9, 2023 |
| Understanding the natural history of Progressive Multifocal Leukoencephalopathy | — | Bethesda, Maryland | Recruiting | Nov 21, 2012 |
All recruiting trials (5)
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PML risk in people with MS treated with ozanimod
This study looks at whether people with MS who take ozanimod develop PML and how often it happens.
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Observational cohort of chronic brain viral infections (including PML)
This project will try immune checkpoint inhibitors in people with chronic central nervous system viral infections like PML to see if they lead to better long-term outcomes.
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Intravenous brincidofovir treatment for progressive multifocal leukoencephalopathy
This trial will test whether intravenous brincidofovir given twice weekly for up to 12 weeks can help adults with progressive multifocal leukoencephalopathy (PML).
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Using a radioactive tracer to detect immune cells in the brain for multiple sclerosis and PML
This study is testing a new radioactive tracer to see if it can help find certain immune cells in the brains of people with multiple sclerosis and PML.
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Understanding the natural history of Progressive Multifocal Leukoencephalopathy
This study looks at how Progressive Multifocal Leukoencephalopathy (PML) affects people with weakened immune systems to better understand the disease and its risk factors.
Related topics
Quick answers
How many Progressive Multifocal Leukoencephalopathy clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (4 trials), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.