Condition

Primary Biliary Cholangitis (PBC) clinical trials and research

• 9Clinical trials
• 29Countries

Newest Primary Biliary Cholangitis (PBC) clinical trials

All recruiting trials (9)

• Biochemical response and health outcomes in people with primary biliary cholangitis

  We will follow adults with primary biliary cholangitis who are taking ursodeoxycholic acid (UDCA) to see if their alkaline phosphatase levels after treatment predict how long they stay free of complications.

  Recruiting RenJi Hospital · Shanghai, Shanghai Municipality · NCT07449793

• Fenofibrate versus UDCA for first-line treatment of primary biliary cholangitis

  This study will test whether fenofibrate works better than the standard medicine UDCA for adults with newly diagnosed primary biliary cholangitis who have not been treated before.

  Recruiting at 2 sites Phase 3 Xijing Hospital of Digestive Diseases · Guangzhou, Guangdong and 1 other locations · NCT07296458

• Early detection of primary biliary cholangitis in people with positive AMA and normal ALP

  This project will test whether clinical features, blood markers, or a liver biopsy can identify early PBC in adults (18-80) who have positive AMA but normal ALP.

  Recruiting Hospital Universitario La Paz · Madrid · NCT07205874

• Multimodal prehabilitation to reduce fatigue in primary biliary cholangitis

  This trial will try a combined program of supervised exercise, nutritional counseling, and mindfulness to reduce fatigue in adults with primary biliary cholangitis who have moderate-to-severe fatigue.

  Recruiting Hospital Clinic of Barcelona · Barcelona, Barcelona · NCT07161245

• Long-term outcomes of primary biliary cholangitis in China

  This project will follow about 4,000 people in China with primary biliary cholangitis to see how symptoms, disease stage, and treatments affect long-term survival.

  Recruiting Beijing Friendship Hospital · Beijing, Select A State Or Province · NCT07149675

• Registry for autoimmune and cholestatic liver diseases in Spain

  This study is collecting information from patients with liver diseases in Spain to better understand these conditions and improve care for those affected.

  Recruiting Asociación Española para el Estudio del Hígado · Barcelona · NCT06767605

• Using Fenofibrate with Ursodeoxycholic Acid for Primary Biliary Cholangitis

  This study is testing whether combining fenofibrate with ursodeoxycholic acid is safe and helpful for people with Primary Biliary Cholangitis who have taken part in a related study before.

  Recruiting Phase 3 Xijing Hospital of Digestive Diseases · Xi'an, Shaanxi · NCT06755541

• Using Fenofibrate with Ursodeoxycholic Acid for Primary Biliary Cholangitis

  This study is testing if taking fenofibrate with ursodeoxycholic acid can be safe and helpful for people with Primary Biliary Cholangitis who have already been part of a related study.

  Recruiting Phase 3 Xijing Hospital of Digestive Diseases · Xi'an, Shaanxi · NCT06755151

• Long-term treatment with elafibranor for adults with primary biliary cholangitis

  This study is testing if the medication elafibranor can help adults with primary biliary cholangitis and cirrhosis avoid getting worse and needing a liver transplant or facing death.

  Recruiting at 140 sites Phase 3 Ipsen · Tucson, Arizona and 197 other locations · NCT06016842

Related topics

Quick answers

How many Primary Biliary Cholangitis (PBC) clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 29 countries. The most sites are in China (5 trials), Spain (4 trials), Argentina (1 trial), Australia (1 trial), Belgium (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 4. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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