Condition
Preclinical Alzheimer's Disease clinical trials and research
Research outlook What's coming for Alzheimer's disease: the next 6 months to 5 yearsAs of November 12, 2026, Find a Trial lists 3 Preclinical Alzheimer's Disease clinical trials that are recruiting, in United States. By phase: Phase 2 (2), Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 1Country
Newest Preclinical Alzheimer's Disease clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Obicetrapib vs. placebo in people at risk for preclinical Alzheimer’s disease | Phase 2 | Nashville, Tennessee | Recruiting | Aug 31, 2026 |
| Tau vaccine AV-1980R in preclinical Alzheimer’s disease | Phase 1 | Boca Raton, Florida and 5 other locations | Recruiting | Sep 8, 2025 |
| Alzheimer’s Tau Platform: a Master Protocol | Phase 2 | Phoenix, Arizona and 6 other locations | Recruiting | May 4, 2025 |
All recruiting trials (3)
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Obicetrapib vs. placebo in people at risk for preclinical Alzheimer’s disease
This study tests whether Obicetrapib can help people who may be at risk for preclinical Alzheimer's disease compare to a placebo.
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Tau vaccine AV-1980R in preclinical Alzheimer’s disease
A Phase 1 study tests a tau-targeting vaccine (AV-1980R) to see if it is safe, tolerable, and can provoke an immune response in older adults who show biomarkers of preclinical Alzheimer’s disease but no cognitive impairment.
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Alzheimer’s Tau Platform: a Master Protocol
This platform study tests tau-directed therapies, alone or with donanemab, in adults 50–80 with late preclinical or early prodromal Alzheimer’s disease to see if they reduce brain tau and slow disease progression.
Related topics
Quick answers
How many Preclinical Alzheimer's Disease clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.