Condition

Persistent Corneal Epithelial Defect clinical trials and research

• 5Clinical trials
• 1New in 30 days
• 17Countries

Newest Persistent Corneal Epithelial Defect clinical trials

All recruiting trials (5)

• TP-06 for Persistent Corneal Epithelial Defects: see if healing improves

  This study tests TP-06 2.0% versus a vehicle to see if it helps adult patients with persistent corneal epithelial defects heal better.

  Recruiting at 6 sites Phase 2 Tarsus Pharmaceuticals, Inc. · Scottsdale, Arizona and 13 other locations · NCT07886268

• Topical insulin drops vs amniotic membrane graft for persistent corneal epithelial defects

  We will test whether topical insulin eye drops or an amniotic membrane graft better helps heal persistent corneal epithelial defects that have not improved with standard treatment.

  Recruiting Phase 4 Al-Shifa Trust Eye Hospital · Rawalpindi, Punjab Province · NCT07561398

• Efficacy and safety of cenegermin eye drops for persistent corneal epithelial defects

  This study tests whether cenegermin eye drops can heal persistent corneal epithelial defects better than a vehicle in adults with PCED.

  Recruiting at 51 sites Phase 3 Dompé Farmaceutici S.p.A · Huntington Beach, California and 76 other locations · NCT07519902

• Topical mesenchymal stem cell secretions for persistent corneal epithelial defects

  This trial will test whether eye drops made from bone-marrow mesenchymal stem cell secretions can help adults whose corneal epithelial defects have not healed with standard treatments.

  Recruiting Phase 2 University of Illinois Chicago · Chicago, Illinois · NCT06919081

• Evaluating NEXAGON® for treating persistent corneal epithelial defects

  This study is testing if NEXAGON® eye gel can help people with stubborn corneal problems that haven't improved with regular treatments.

  Recruiting at 28 sites Phase 2 Glaukos Corporation · Dothan, Alabama and 27 other locations · NCT05966493

Quick answers

How many Persistent Corneal Epithelial Defect clinical trials are recruiting right now?

5, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 17 countries. The most sites are in United States (4 trials), Germany (2 trials), Italy (2 trials), Spain (2 trials), Mexico (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →