Condition

Non-small Cell Lung Cancer Stage IV clinical trials and research

• 5Clinical trials
• 2Countries

Newest Non-small Cell Lung Cancer Stage IV clinical trials

All recruiting trials (5)

• First-Line Ipilimumab, Nivolumab, and IL-15 Superagonist in Advanced or Recurrent NSCLC

  A phase Ib/II study tests whether adding nogapendekin alfa inbakicept to nivolumab and ipilimumab helps people with stage IV or recurrent non-small cell lung cancer.

  Recruiting Phase 1/2 Washington University School of Medicine · St Louis, Missouri · NCT07355205

• Proteomic-guided, risk-adapted therapy for advanced non-small cell lung cancer

  This trial tests whether using a proteomic test plus a toxicity risk tool to pick immune checkpoint inhibitor–based treatment can improve 12-month progression-free survival for people with previously untreated advanced non-small cell lung cancer.

  Recruiting at 4 sites Phase 2 University of California, Davis · Chico, California and 3 other locations · NCT07250477

• Pulmonary rehabilitation for people who survived advanced non-small cell lung cancer

  This research will try an eight-week pulmonary rehabilitation program to see if it helps people with advanced non-small cell lung cancer breathe easier and have more energy.

  Recruiting Phase 2 Case Comprehensive Cancer Center · Cleveland, Ohio · NCT07104630

• First human use of 177Lu‑AKIR001 for CD44v6‑positive advanced cancers

  This trial tests a Lutetium‑177 radiolabeled drug (AKIR001) in adults with advanced, irresectable CD44v6‑expressing solid tumors who have no reasonable systemic treatment options.

  Recruiting Early Phase 1 Karolinska University Hospital · Stockholm, Stockholm County · NCT06639191

• New treatment for advanced non-small-cell lung cancer using a virus and chemotherapy

  This study is testing a new treatment that combines a special virus and chemotherapy to see if it can help people with advanced lung cancer who haven't responded to previous treatments.

  Recruiting at 15 sites Phase 2 Genelux Corporation · Bullhead City, Arizona and 14 other locations · NCT06463665

Related topics

Quick answers

How many Non-small Cell Lung Cancer Stage IV clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (4 trials), Sweden (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1/2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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