Condition

Myelodysplastic Syndromes, High Risk clinical trials and research

• 2Clinical trials
• 1New in 30 days
• 2Countries

All recruiting trials (2)

• Sonrotoclax plus azacitidine in high-risk MDS with increased blasts-2

  This study tests whether adding sonrotoclax to azacitidine can help people with newly diagnosed high-risk MDS with increased blasts-2 see better disease control and tolerable safety.

  Recruiting Phase 1/2 Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality and 5 other locations · NCT07885397

• Higher-dose UM171 to improve cord blood stem cell transplants

  This will try a higher lab dose of UM171 to expand umbilical cord blood stem cells for adults with high-risk leukemia or myelodysplasia who lack a suitable donor to see if they recover blood counts faster and have fewer complications after transplant.

  Recruiting Phase 1/2 Ciusss de L'Est de l'Île de Montréal · Montreal, Quebec · NCT07301866

Quick answers

How many Myelodysplastic Syndromes, High Risk clinical trials are recruiting right now?

2, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in China (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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