Condition
Monogenic Obesity clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Monogenic Obesity clinical trials that are recruiting, at sites in 6 countries (most in France (2), Germany (2), Netherlands (1)). By phase: Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 6Countries
Newest Monogenic Obesity clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Once-weekly semaglutide for weight loss in adolescents with monogenic obesity | — | Paris and 6 other locations | Recruiting | Dec 24, 2025 |
| Mibavademab for obesity caused by leptin (LEP) gene mutations in children, adolescents, and adults | Phase 3 | Ulm and 2 other locations | Recruiting | Oct 24, 2025 |
| Evaluating WEGOVY treatment for adults with genetic obesity | — | Paris and 1 other locations | Recruiting | Apr 23, 2024 |
All recruiting trials (3)
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Once-weekly semaglutide for weight loss in adolescents with monogenic obesity
This study tests whether once-weekly semaglutide 2.4 mg together with a reduced-calorie diet and increased activity helps adolescents with monogenic obesity lose weight, reduce hunger, and improve quality of life over 68 weeks.
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Mibavademab for obesity caused by leptin (LEP) gene mutations in children, adolescents, and adults
This trial will try mibavademab in children, adolescents, and adults with leptin gene–related obesity to help control body weight and check safety.
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Evaluating WEGOVY treatment for adults with genetic obesity
This study is testing how well WEGOVY helps adults with a rare genetic obesity condition manage their weight and related health issues.
Related topics
Quick answers
How many Monogenic Obesity clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 6 countries. The most sites are in France (2 trials), Germany (2 trials), Netherlands (1 trial), Spain (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.