Condition

Methylmalonic Acidemia clinical trials and research

• 4Clinical trials
• 10Countries

Newest Methylmalonic Acidemia clinical trials

All recruiting trials (4)

• Long-term evaluation of mRNA-3705 for treating methylmalonic acidemia

  This study is testing if a new treatment called mRNA-3705 is safe and effective for people with methylmalonic acidemia who have already tried it in previous studies.

  Recruiting at 11 sites Phase 1/2 ModernaTX, Inc. · Los Angeles, California and 11 other locations · NCT05295433

• Observing the effects of Carbaglu® in treating MMA and PA in patients

  This study is testing how safe Carbaglu® is for treating high ammonia levels in people with Methylmalonic Acidemia and Propionic Acidemia, both kids and adults.

  Recruiting at 5 sites Recordati Group · Washington D.C., District of Columbia and 4 other locations · NCT05040178

• Long-term management of organic acidemia with CARBAGLU®

  This study looks at how well carglumic acid helps people with propionic acidemia and methylmalonic acidemia over a long time, while also talking to patients and caregivers about their experiences.

  Recruiting at 31 sites Recordati Group · Bordeaux and 31 other locations · NCT04176523

• Observational study of Methylmalonic Acidemia

  This study looks at how often complications like metabolic stroke and developmental delays happen in people of all ages with Methylmalonic Acidemia to help improve future treatments.

  Recruiting at 2 sites National Institutes of Health Clinical Center (CC) · Washington D.C., District of Columbia and 2 other locations · NCT00078078

Related topics

Quick answers

How many Methylmalonic Acidemia clinical trials are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in United States (3 trials), France (2 trials), Spain (2 trials), United Kingdom (2 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →