Condition

Malaria Falciparum clinical trials and research

• 6Clinical trials
• 7Countries

Newest Malaria Falciparum clinical trials

All recruiting trials (6)

• First-in-human dose-escalation of a monoclonal antibody for malaria safety in healthy adults

  This study tests whether GSK4425689A is safe and tolerable and how it behaves in the body after IV or SC dosing in healthy adults.

  Recruiting Phase 1 GlaxoSmithKline · Manchester · NCT07646353

• New antimalarial drug GSK3772701 in adults with uncomplicated falciparum malaria

  A Phase 2A study tests whether the new drug GSK3772701 can be safely given in different doses to adults with uncomplicated falciparum malaria to see if it works.

  Recruiting at 2 sites Phase 2 GlaxoSmithKline · Lambaréné and 1 other locations · NCT07545681

• Combining dihydroartemisinin‑piperaquine and a single low dose of primaquine to reduce malaria in high-transmission communities in Eastern Ghana

  This will test whether giving whole communities dihydroartemisinin‑piperaquine plus a single low dose of primaquine can reduce malaria infections in people aged 3 months and older who live in high-transmission communities in Eastern Ghana.

  Recruiting Noguchi Memorial Institute for Medical Research · Accra, Eastern Region · NCT07389057

• Single ascending long-acting injectable doses of MMV055 alone and with MMV371 in healthy adults

  This trial will test single ascending long-acting injectable doses of MMV055, alone and combined with MMV371, in healthy adults to check safety, tolerability, and how the drugs behave in the body.

  Recruiting Phase 1 Medicines for Malaria Venture · Nottingham · NCT07011511

• Serology-guided radical treatment to reduce Plasmodium vivax relapses in Ethiopia and Madagascar

  This project will use an antibody blood test to find people recently infected with P. vivax and give G6PD-tested patients primaquine plus a blood-stage antimalarial to try to prevent relapses in selected communities.

  Recruiting Phase 3 London School of Hygiene and Tropical Medicine · Addis Ababa and 1 other locations · NCT06923592

• PfSPZ-LARC2 vaccine for preventing falciparum malaria in healthy adults

  This project will test whether the PfSPZ-LARC2 vaccine, given by direct venous injection, can safely protect healthy adults with no prior malaria from a controlled malaria infection.

  Recruiting Phase 1 Sanaria Inc. · Tübingen · NCT06862453

Related topics

Quick answers

How many Malaria Falciparum clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United Kingdom (2 trials), Ethiopia (1 trial), Madagascar (1 trial), Gabon (1 trial), Uganda (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →