Condition
Locally Recurrent Rectal Cancer clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Locally Recurrent Rectal Cancer clinical trials that are recruiting, at sites in 2 countries (most in China (2), Netherlands (1)). By phase: Phase 2 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 2Countries
Newest Locally Recurrent Rectal Cancer clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Radiotherapy dose escalation for unresectable locally recurrent rectal cancer | — | Maastricht, Limburg and 5 other locations | Recruiting | Jul 22, 2026 |
| Short-course radiation with liposomal irinotecan, anti–PD-1, and targeted therapy for locally recurrent rectal cancer | Phase 2 | Shanghai, Shanghai Municipality | Recruiting | Sep 19, 2025 |
| Comparing two types of radiotherapy for locally recurrent rectal cancer | Phase 2 | Shanghai, Shanghai Municipality | Recruiting | Apr 15, 2025 |
All recruiting trials (3)
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Radiotherapy dose escalation for unresectable locally recurrent rectal cancer
This study tests whether increasing radiotherapy dose is safe and feasible for people with unresectable locally recurrent rectal cancer who cannot have surgery.
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Short-course radiation with liposomal irinotecan, anti–PD-1, and targeted therapy for locally recurrent rectal cancer
This trial will test whether short-course radiation plus liposomal irinotecan (NALIRIF) with 5‑FU/leucovorin, an anti–PD‑1 drug, and targeted therapy can shrink pelvic recurrences in patients with locally recurrent rectal cancer who have already failed oxaliplatin.
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Comparing two types of radiotherapy for locally recurrent rectal cancer
This study is testing if a new type of radiotherapy combined with immunotherapy can help people with locally recurrent rectal cancer live longer without their cancer getting worse compared to standard radiotherapy.
Quick answers
How many Locally Recurrent Rectal Cancer clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in China (2 trials), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.