Condition

Locally Advanced (Unresectable) or Metastatic Solid Tumors clinical trials and research

• 7Clinical trials
• 4Countries

Newest Locally Advanced (Unresectable) or Metastatic Solid Tumors clinical trials

All recruiting trials (7)

• Test a combination of SSGJ-705 and SSGJ-612 (with or without chemotherapy) in advanced HER2-expressing solid cancers

  This phase 2 study tests whether SSGJ-705 plus SSGJ-612, with or without chemotherapy, can help adults with advanced HER2-expressing solid tumors like colorectal, urothelial, breast, gastric, or biliary cancers.

  Recruiting Phase 2 Shenyang Sunshine Pharmaceutical Co., LTD. · Hangzhou, Zhejiang · NCT07646626

• Targeted cancer therapy using NEOK002 for select solid tumors

  This first-in-human study tests NEOK002, a bispecific antibody-drug conjugate, in people with locally advanced or metastatic solid tumors to see if it is safe and tolerable.

  Recruiting at 10 sites Phase 1 NEOK Bio, Inc. · Orlando, Florida and 9 other locations · NCT07612189

• NEOK001: a new B7-H3 and ROR1-targeting cancer treatment given by IV infusion

  This early-phase study tests NEOK001, a bispecific antibody-drug conjugate, in people with locally advanced or metastatic solid tumors to see if it is safe and how it behaves in the body.

  Recruiting at 9 sites Phase 1 NEOK Bio, Inc. · New York, New York and 8 other locations · NCT07612176

• Evaluating TXN10128 for patients with solid tumors

  This study is testing a new treatment called TXN10128 to see if it's safe and effective for people with advanced solid tumors, both on its own and when combined with other cancer drugs.

  Recruiting at 6 sites Phase 1 Txinno Bioscience Inc. · Seongnam-si, Gyeonggi-do and 5 other locations · NCT05978492

• SG1906 treatment for certain solid tumors

  This study is testing a new treatment called SG1906 for people with certain hard-to-treat solid tumors to see if it is safe and effective.

  Recruiting at 9 sites Phase 1 Hangzhou Sumgen Biotech Co., Ltd. · Beijing, Beijing Municipality and 8 other locations · NCT05857332

• Testing IBI354 in patients with advanced solid tumors

  This study is testing a new drug called IBI354 to see if it is safe and effective for people with advanced solid tumors that can't be removed by surgery.

  Recruiting at 2 sites Phase 1/2 Innovent Biologics (Suzhou) Co. Ltd. · Randwick, New South Wales and 5 other locations · NCT05636215

• Testing IBI343 in patients with advanced solid tumors

  This study is testing a new drug called IBI343 to see if it is safe and effective for people with advanced solid tumors that can't be removed by surgery.

  Recruiting at 38 sites Phase 1 Innovent Biologics (Suzhou) Co. Ltd. · Austin, Texas and 38 other locations · NCT05458219

Quick answers

How many Locally Advanced (Unresectable) or Metastatic Solid Tumors clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in China (4 trials), United States (3 trials), Australia (2 trials), South Korea (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 5, Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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