Condition

Large B-Cell Lymphoma (LBCL) clinical trials and research

• 6Clinical trials
• 18Countries

Newest Large B-Cell Lymphoma (LBCL) clinical trials

All recruiting trials (6)

• CT1190B cell therapy for relapsed/refractory large B-cell lymphoma

  This study tests CT1190B cells in adults with relapsed or refractory LBCL to see if they are safe and can help shrink tumors.

  Recruiting Phase 1/2 UCARsgen Biotech Limited · Shanghai, Shanghai Municipality and 2 other locations · NCT07823829

• Academic anti-CD19 CAR-T for relapsed or refractory large B‑cell lymphoma

  This project tests whether a locally manufactured anti‑CD19 CAR‑T cell therapy works and is safe for adults whose large B‑cell lymphoma has relapsed or not responded to prior treatment.

  Recruiting N.N. Alexandrov National Cancer Centre · Lyasny, Minsk Oblast · NCT07524816

• Pola-ZR-Glo for older patients with large B‑cell lymphoma

  This trial will try combining polatuzumab vedotin, zanubrutinib, lenalidomide, and glofitamab as first-line treatment for people aged 70 and older with newly diagnosed large B‑cell lymphoma who are unfit for standard chemo or decline immunochemotherapy.

  Recruiting Phase 2 Ruijin Hospital · Shanghai · NCT07514169

• Adding CLS-015 to anti-CD19 CAR-T therapy for large B‑cell lymphoma during lymphodepletion

  This trial tests whether giving CLS-015 (an enzyme that breaks down NETs) alongside anti‑CD19 CAR‑T therapy helps adults with large B‑cell lymphoma who have stable or progressing disease at the time of lymphodepletion.

  Recruiting Phase 1 Tel-Aviv Sourasky Medical Center · Tel Aviv · NCT07361224

• Treatment with AZD0486 for patients with relapsed B-cell lymphoma

  This study is testing a new treatment called AZD0486 to see if it can help adults with relapsed B-cell lymphoma feel better and stay safe after trying other therapies.

  Recruiting at 80 sites Phase 2 AstraZeneca · Phoenix, Arizona and 93 other locations · NCT06526793

• CD19 CAR-T therapy for B-cell non-Hodgkin's lymphoma

  This study is testing a new CAR-T cell therapy for people with B-cell non-Hodgkin's lymphoma who don't want to have standard chemotherapy, to see how safe and effective it is.

  Recruiting Phase 2 Zhejiang University · Hangzhou, Zhejiang · NCT04661020

Related topics

Quick answers

How many Large B-Cell Lymphoma (LBCL) clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 18 countries. The most sites are in China (4 trials), Israel (1 trial), Australia (1 trial), Brazil (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 1: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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