Condition
High Risk Localized Prostate Cancer clinical trials and research
As of November 12, 2026, Find a Trial lists 3 High Risk Localized Prostate Cancer clinical trials that are recruiting, at sites in 3 countries (most in Netherlands (1), China (1), United States (1)). By phase: Phase 2 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 3Countries
Newest High Risk Localized Prostate Cancer clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Prospective Prostate Cancer Infrastructure for High-Risk and Metastatic Disease | — | Nijmegen | Recruiting | May 1, 2026 |
| Adding 177Lu-PSMA-617 to EBRT and short ADT for high-risk localized prostate cancer | Phase 2 | Baltimore, Maryland | Recruiting | Apr 24, 2026 |
| Darolutamide plus hormone therapy before prostate removal for men with high-risk localized prostate cancer | Phase 2 | Hefei, Anhui and 22 other locations | Recruiting | Mar 4, 2026 |
All recruiting trials (3)
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Prospective Prostate Cancer Infrastructure for High-Risk and Metastatic Disease
This study will collect long-term real-world data and biomaterials from men with high-risk localized or metastatic hormone-sensitive prostate cancer to understand everyday treatment patterns and quality of life.
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Adding 177Lu-PSMA-617 to EBRT and short ADT for high-risk localized prostate cancer
This study tests whether adding a PSMA-targeted therapy before and during standard radiation plus a shorter 6-month hormone therapy is safe and may improve outcomes for men with high-risk localized prostate cancer.
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Darolutamide plus hormone therapy before prostate removal for men with high-risk localized prostate cancer
This study tests whether adding darolutamide to standard hormone (androgen-deprivation) therapy for 12 or 24 weeks before prostate removal helps men with high-risk localized prostate cancer.
Quick answers
How many High Risk Localized Prostate Cancer clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in Netherlands (1 trial), China (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.