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HER2-positive Early Breast Cancer clinical trials and research

• 4Clinical trials
• 2Countries

Newest HER2-positive Early Breast Cancer clinical trials

All recruiting trials (4)

• Intensified HER2-targeted treatment for people with a suboptimal response to initial dual HER2 therapy and chemotherapy

  This trial will try stronger targeted drug combinations for people with HER2-positive early breast cancer who don't respond well to initial dual HER2-targeted therapy plus chemotherapy.

  Recruiting Phase 2 Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou · NCT07340398

• Comparing two chemotherapy regimens for HER2-positive early breast cancer

  This study is testing two different chemotherapy treatments to see which one works better for women with early-stage HER2-positive breast cancer after surgery.

  Recruiting Phase 3 Fudan University · Shanghai, Shanghai Municipality · NCT05883852

• Neoadjuvant therapy for HER2-positive early breast cancer

  This study is testing if a new drug called trastuzumab-deruxtecan can work better than standard chemotherapy for people with early HER2-positive breast cancer to see if it helps them respond better to treatment.

  Recruiting at 40 sites Phase 2 Women's Cancer Study Group GmbH · Baden-Baden, Baden-Wurttemberg and 43 other locations · NCT05704829

• Neoadjuvant therapy guided by drug screening for HER2 positive early breast cancer

  This study is testing if certain patients with early HER2-positive breast cancer can skip chemotherapy by using drug screening to find out which treatments work best for them.

  Recruiting Phase 1/2 Peking University People's Hospital · Beijing, Beijing Municipality · NCT04750122

Related topics

Quick answers

How many HER2-positive Early Breast Cancer clinical trials are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in China (3 trials), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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