Condition
Epileptic Encephalopathy clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Epileptic Encephalopathy clinical trials that are recruiting, at sites in 7 countries (most in Italy (3), United States (3), France (2)). By phase: Phase 1/2 (1), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 7Countries
Newest Epileptic Encephalopathy clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| S230815 for children with KCNT1-related developmental and epileptic encephalopathy | Phase 1/2 | Orange, California and 14 other locations | Recruiting | Nov 13, 2025 |
| Elsunersen treatment for infants with early-onset SCN2A-related epileptic encephalopathy | Phase 3 | San Diego, California and 9 other locations | Recruiting | Jun 13, 2025 |
| Home monitoring of seizures using a wearable EEG device for rare epilepsies | — | Roma, Italy and 3 other locations | Recruiting | Mar 4, 2025 |
| Register of patients with neonatal-onset epileptic encephalopathy | — | Angers and 14 other locations | Recruiting | Mar 17, 2021 |
| Understanding the genetics behind epilepsy and related disorders | — | Boston, Massachusetts | Recruiting | May 21, 2013 |
All recruiting trials (5)
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S230815 for children with KCNT1-related developmental and epileptic encephalopathy
This study will test whether the investigational medicine S230815 is safe, well tolerated, and affects seizures and related symptoms in children aged 2–12 who have KCNT1-related developmental and epileptic encephalopathy.
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Elsunersen treatment for infants with early-onset SCN2A-related epileptic encephalopathy
This trial tests whether elsunersen can reduce seizures and is safe in infants and young children with early-onset SCN2A-related developmental and epileptic encephalopathy who have gain-of-function variants.
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Home monitoring of seizures using a wearable EEG device for rare epilepsies
This study is testing a new wearable device that helps people with rare types of epilepsy monitor their seizures at home to see if it can improve their treatment and care.
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Register of patients with neonatal-onset epileptic encephalopathy
This study is trying to gather information about babies with neonatal-onset epileptic encephalopathy to see how genetic factors, especially changes in the KCNQ2 gene, affect their condition and help improve treatment options.
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Understanding the genetics behind epilepsy and related disorders
This study is trying to find out how genes affect epilepsy and similar disorders in kids to help improve their diagnosis and treatment.
Related topics
Quick answers
How many Epileptic Encephalopathy clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 7 countries. The most sites are in Italy (3 trials), United States (3 trials), France (2 trials), Japan (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.