Condition
Chronic Granulomatous Disease (CGD) clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Chronic Granulomatous Disease (CGD) clinical trials that are recruiting, at sites in 5 countries (most in United States (3), Germany (1), Spain (1)). By phase: Phase 1/2 (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 5Countries
Newest Chronic Granulomatous Disease (CGD) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Open-label gene therapy for p47-CGD in adults and children over 18 months | Phase 1/2 | Ulm and 2 other locations | Recruiting | Sep 17, 2026 |
| Assessing antibodies and cytokines in patients with Chronic Granulomatous Disease | — | Montgomery, Alabama and 51 other locations | Recruiting | Sep 20, 2024 |
| Base editing of blood stem cells to fix the CYBB mutation in X-linked chronic granulomatous disease. | Phase 1/2 | Bethesda, Maryland | Recruiting | Mar 22, 2024 |
| Evaluation of patients with immune function abnormalities | — | Bethesda, Maryland | Recruiting | Aug 10, 2005 |
All recruiting trials (4)
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Open-label gene therapy for p47-CGD in adults and children over 18 months
This gene therapy study tests SGX-001 to help people with p47-CGD caused by NCF1 mutations.
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Assessing antibodies and cytokines in patients with Chronic Granulomatous Disease
This study looks at the levels of certain antibodies and inflammation markers in people with Chronic Granulomatous Disease to better understand their immune response.
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Base editing of blood stem cells to fix the CYBB mutation in X-linked chronic granulomatous disease.
This trial will try base-editing a person's own blood stem cells to fix a specific CYBB mutation in adult men with X-linked chronic granulomatous disease.
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Evaluation of patients with immune function abnormalities
This study is testing how immune problems affect people with conditions like XSCID and CGD to help find better treatments and understand their health over time.
Quick answers
How many Chronic Granulomatous Disease (CGD) clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 5 countries. The most sites are in United States (3 trials), Germany (1 trial), Spain (1 trial), Switzerland (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 2. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.