Condition

Advanced Non-small Cell Lung Cancer (NSCLC) clinical trials and research

• 7Clinical trials
• 3Countries

Newest Advanced Non-small Cell Lung Cancer (NSCLC) clinical trials

All recruiting trials (7)

• Befotertinib plus chemo with MRD-guided escalation for EGFR-mutant NSCLC

  This phase 2 trial tests whether starting befotertinib and then using MRD results to guide adding chemotherapy improves outcomes for adults with EGFR-mutant advanced NSCLC.

  Recruiting Phase 2 Guangzhou University of Traditional Chinese Medicine · Guangzhou, Guangdong and 1 other locations · NCT07709585

• A Phase II test of AK146D1 with AK112 in advanced NSCLC

  This phase II study tests whether AK146D1 together with AK112 or other cancer therapies can be safely given and help treat adults with advanced non-small cell lung cancer.

  Recruiting Phase 2 Akeso · Guangzhou, Guangdong · NCT07669779

• Liquid biopsy at diagnosis for advanced NSCLC

  We’re testing whether a blood test (liquid biopsy) done early can speed up getting usable molecular information for adults with suspected advanced NSCLC.

  Recruiting Regina Elena Cancer Institute · Roma, RM · NCT07649629

• AMT-116 with AK112 in advanced NSCLC

  This study tests whether AMT-116 plus Ivonescimab (AK112) is safe and helpful for adults with advanced non-small cell lung cancer who can’t be cured with surgery or standard treatment.

  Recruiting Phase 1/2 Multitude Therapeutics Inc. · Guangzhou, Guangdong and 1 other locations · NCT07590531

• Finding better ways to detect resistance to antibody‑drug conjugates in solid tumors and identify useful biomarkers

  This trial tests whether tissue and blood biomarkers collected before and after treatment can reveal why antibody‑drug conjugates stop working in adults with advanced breast, gastric, urothelial, or non‑small cell lung cancer.

  Recruiting Phase 2 Unicancer · Villejuif · NCT07259226

• BC008-1A for advanced esophageal cancer and non-small cell lung cancer

  This study will try giving BC008-1A by IV every three weeks to see if it is safe and helps people with advanced esophageal cancer or non-small cell lung cancer with PD‑L1 expression.

  Recruiting Phase 1 Sichuan Luzhou Buchang Biopharmaceutical Co., Ltd. · Tianjin · NCT06773507

• Vorolanib treatment for advanced non-small cell lung cancer patients

  This study is testing if Vorolanib can help patients with advanced non-small cell lung cancer who have already tried other treatments feel better and live longer.

  Recruiting Phase 2 Sun Yat-sen University · Guangzhou, Guangdong · NCT06728852

Related topics

Quick answers

How many Advanced Non-small Cell Lung Cancer (NSCLC) clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in China (5 trials), Italy (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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